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You are seeing a 65-year-old male in a primary care setting who has presented with non-specific symptoms such as malaise, fatigue, nausea, weight loss and abdominal pain. During examination you note the presence of a palpable left lobe of the liver and splenomegaly. You also note the presence of spider naevi, palmar erythema, white nails, abnormal bruising and ascites. What is the most likely diagnosis?